Description

tert-Butyl Benzylcyanomethylcarbamate is a specialized carbamate derivative and a valuable synthetic intermediate in organic chemistry. Its molecular structure, featuring both a tert-butyloxycarbonyl (Boc) protecting group and a benzyl-protected cyanoacetamide moiety, makes it a critical building block for the controlled synthesis of complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It enables the efficient construction of peptide mimetics, heterocycles, and other pharmacologically active scaffolds where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetic Synthesis: Used to introduce protected amino acid analogs and non-natural amino acid residues into peptide chains, enhancing metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and insecticides, leveraging its carbamate functionality.
• Chemical Biology Probes: Employed in the creation of activity-based probes (ABPs) and other tools for studying enzyme function and mechanism.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects requiring specific, protected molecular architectures.
• Academic & Industrial R&D: Utilized in methodological development and exploratory chemistry for new reaction pathways and compound libraries.

Basic Information

Product Name	tert-Butyl Benzylcyanomethylcarbamate
CAS No.	194207-87-9
Molecular Formula	C14H18N2O2
Molecular Weight	246.31 g/mol
Synonyms	Benzyl (tert-butoxycarbonyl)cyanoacetate; tert-Butyl (benzyloxycarbonyl)(cyano)methylcarbamate; (Benzyloxycarbonyl)(cyano)acetic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-N-(benzyloxycarbonyl)aminoacetonitrile; Cyanoacetic acid, N-(tert-butoxycarbonyl)-, benzyl ester; BOC-Cya-OBzl; 194207-87-9
EINECS	Contact for details

Quality Control

Our tert-Butyl Benzylcyanomethylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.