Description

Glycine, n-[[[(1,1-Dimethylethoxy)carbonyl]amino]carbonyl]- (9Ci) is a specialized, protected amino acid derivative of significant value in advanced organic synthesis. This compound matters as a crucial building block for the controlled introduction of glycine moieties in complex molecular architectures, particularly in peptide and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for synthesizing novel active compounds and intermediates where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key protected precursor in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate modified amino acid structures.
• Bioconjugation & Linker Chemistry: Acts as a versatile spacer or linker molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocycles and unnatural amino acid derivatives.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) protecting group allows for orthogonal deprotection strategies in multi-step synthetic sequences.

Basic Information

Product Name	Glycine, n-[[[(1,1-Dimethylethoxy)carbonyl]amino]carbonyl]- (9Ci)
CAS No.	194163-39-8
Molecular Formula	C8H14N2O5
Molecular Weight	218.21 g/mol
Synonyms	N-[(tert-Butoxycarbonyl)carbamoyl]glycine; N-(Boc-carbamoyl)glycine; Glycine, N-[(tert-butoxycarbonyl)carbamoyl]-; (Boc-NH-CO)NH-CH2-COOH; 2-[[[(2-Methylpropan-2-yl)oxycarbonyl]amino]carbamoylamino]acetic acid; tert-Butyl N-(carbamoylcarbamoyl)carbamate; Boc-NH-CO-NH-CH2-COOH
EINECS	Contact for details

Quality Control

Our Glycine, n-[[[(1,1-Dimethylethoxy)carbonyl]amino]carbonyl]- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. While typically supplied in research-grade purity, specifications can be tailored to meet specific project requirements. Certificates of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccant or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.