Description

3-Bromo-4-Fluorophenylacetic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily utilized by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo- and fluoro-substituted phenylacetic acid motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that require halogenated aromatic components.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its stable aromatic core and halogen substituents.
• Peptide Mimetics & Bioconjugation: The carboxylic acid functional group allows for coupling reactions to create peptide analogs or linker molecules for bioconjugation applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for custom synthesis projects requiring specific halogenated phenylacetic acid derivatives.
• Academic & Industrial Research: Employed in chemical research for studying structure-activity relationships (SAR) and developing new synthetic methodologies involving cross-coupling reactions.

Basic Information

Product Name	3-Bromo-4-Fluorophenylacetic Acid
CAS No.	194019-11-9
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	(3-Bromo-4-fluorophenyl)acetic Acid; 2-(3-Bromo-4-fluorophenyl)acetic Acid; 3-Bromo-4-fluoro-benzeneacetic Acid; α-(3-Bromo-4-fluorophenyl)acetic Acid; 4-Fluoro-3-bromophenylacetic Acid; NSC 405124; BRN 2809923
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.