Description

Gelatinase A is a specialized matrix metalloproteinase (MMP-2) enzyme critical for the targeted degradation of type IV collagen and gelatin substrates. This high-purity biochemical is essential for research and development in fields requiring precise proteolytic activity. It is primarily utilized by biotechnology, pharmaceutical, and academic research institutions for applications in cell culture, tissue remodeling studies, and biochemical assay development.

Application

• Biomedical Research: Used in studies of extracellular matrix (ECM) degradation, cancer metastasis, and angiogenesis.
• Cell Culture & Tissue Engineering: Facilitates the detachment of cells from culture dishes and the digestion of tissues for primary cell isolation.
• Diagnostic Assay Development: Serves as a key component or target in enzymatic activity assays and inhibitor screening platforms.
• Pharmaceutical R&D: Employed in the discovery and validation of novel MMP-2 inhibitor drugs for therapeutic applications.
• Protein Biochemistry: Used for the controlled cleavage of fusion proteins or the analysis of protein structure and function.

Basic Information

Product Name	Gelatinase A
CAS No.	193807-58-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MMP-2; 72 kDa Gelatinase; Type IV Collagenase; Matrix Metalloproteinase-2; Gelatinase A, Human; Neutrophil Gelatinase; CLG4; TBE-1
EINECS	Contact for details

Quality Control

Our Gelatinase A is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and absence of contaminating proteases. We adhere to relevant guidelines for research-grade biochemicals to support reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture condensation. For optimal performance, prepare aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Cleaves gelatin / type IV collagen
Purity (SDS-PAGE)	> 90%
Specific Activity	Contact for details
Protein Concentration	Contact for details
Endotoxin Level	< 1.0 EU/µg (where applicable)
Storage Buffer	Tris, CaCl2, pH 7.5 (typical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.