Description

Ethanone, 2,2,2-Trifluoro-1-(2-Hydroxy-6-Methoxyphenyl)- (9Ci) CAS NO 193738-66-8 is a specialized trifluoromethyl ketone derivative featuring a hydroxy-methoxy substituted phenyl ring, making it a valuable fluorinated building block. This compound is significant for its role in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine atoms is crucial for modulating biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a trifluoromethyl ketone moiety.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and target binding.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced materials with unique thermal or chemical resistance.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis, leveraging the electron-withdrawing trifluoromethyl group.
• Fluorine Chemistry Studies: A valuable reference standard and starting material for academic and industrial research in organofluorine chemistry.
• Chemical Biology Probes: Utilized in the design of enzyme inhibitors and molecular probes for biochemical and pharmacological studies.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Hydroxy-6-Methoxyphenyl)- (9Ci)
CAS No.	193738-66-8
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-hydroxy-6-methoxyphenyl)ethanone; 1-(2-Hydroxy-6-methoxyphenyl)-2,2,2-trifluoroethanone; 2-Hydroxy-6-methoxy-α,α,α-trifluoroacetophenone; 2',6'-Dihydroxy-2,2,2-trifluoroacetophenone (ambiguous); TFHA derivative; Trifluoromethyl ketone derivative; o-Hydroxy-m-methoxy-α,α,α-trifluoroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(2-Hydroxy-6-Methoxyphenyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades, from technical to high-purity research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Research Grade)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.