Description

(S)-1-n-Cbz-3-Cyanopyrrolidine is a high-purity chiral building block and key synthetic intermediate. This compound is critical for the development of novel pharmaceuticals, particularly in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. It is primarily used by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers specializing in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, including protease inhibitors and other biologically active compounds.
• Asymmetric Synthesis: Used as a versatile building block for constructing stereochemically defined pyrrolidine scaffolds in medicinal chemistry.
• Peptidomimetics Research: Serves as a constrained proline analog for the design and development of novel peptidomimetic drug candidates.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up development.
• Academic Research: A valuable reagent for university and institutional research in organic methodology development and total synthesis.

Basic Information

Product Name	(S)-1-n-Cbz-3-Cyanopyrrolidine
CAS No.	193693-69-5
Molecular Formula	C13H14N2O2
Molecular Weight	230.26 g/mol
Synonyms	(S)-1-[(Benzyloxy)carbonyl]-3-cyanopyrrolidine; (S)-1-Carbobenzoxy-3-cyanopyrrolidine; (S)-1-Cbz-3-cyanopyrrolidine; (S)-N-Cbz-3-cyanopyrrolidine; (S)-3-Cyanopyrrolidine-1-carboxylic acid benzyl ester; (S)-1-(Benzyloxycarbonyl)-3-cyanopyrrolidine; (S)-1-CBZ-3-CYANO-PYRROLIDINE; (S)-1-Carbobenzyloxy-3-cyanopyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-1-n-Cbz-3-Cyanopyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate production. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.