Description

2-Fluoro-2-Methyl-3-Oxo-3-Phenyl-Propionic Acid Ethyl Ester is a high-value fluorinated β-keto ester building block, prized for its unique molecular architecture that enables the synthesis of complex, biologically active molecules. Its core value proposition lies in providing a versatile scaffold for introducing fluorine and ketone functionalities, which are critical for modulating the potency, metabolic stability, and selectivity of target compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel heterocycles and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Organic Synthesis Building Block: Serves as a versatile precursor for Claisen condensations, Michael additions, and cyclization reactions to create complex heterocyclic compounds.
• Material Science Research: Investigated as a monomer or additive for synthesizing specialty polymers with tailored optical or electronic properties.
• Fluorine Chemistry Studies: An important compound for academic and industrial research exploring the effects of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	2-Fluoro-2-Methyl-3-Oxo-3-Phenyl-Propionic Acid Ethyl Ester
CAS No.	193482-31-4
Molecular Formula	C₁₂H₁₃FO₃
Molecular Weight	224.23 g/mol
Synonyms	Ethyl 2-Fluoro-2-methyl-3-oxo-3-phenylpropanoate; 3-Phenyl-2-fluoro-2-methyl-3-oxopropionic Acid Ethyl Ester; 2-Fluoro-2-methyl-3-oxo-3-phenylpropionic acid ethyl ester; Ethyl 2-fluoro-2-methyl-3-oxo-3-phenylpropionate; β-Keto ester fluorinated derivative; 193482-31-4; Propanoic acid, 2-fluoro-2-methyl-3-oxo-3-phenyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-2-Methyl-3-Oxo-3-Phenyl-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.