Description

n-Octadecanoyl Coenzyme A Lithium Salt is a high-purity, long-chain fatty acyl-CoA ester, a critical biochemical reagent for studying lipid metabolism. This compound serves as a vital substrate and intermediate in enzymatic assays and metabolic pathway research, enabling precise investigation of fatty acid activation and β-oxidation processes. It is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and diagnostic kit production who require reliable, well-characterized coenzyme A derivatives.

Application

• Enzymology Research: As a defined substrate for studying acyl-CoA synthetases, thioesterases, and other enzymes involved in lipid biosynthesis and degradation.
• Metabolic Pathway Analysis: A key intermediate for in vitro reconstitution and analysis of mitochondrial β-oxidation and peroxisomal fatty acid α-oxidation pathways.
• Drug Discovery & Screening: Used in high-throughput assays to identify and characterize inhibitors or modulators of lipid-metabolizing enzymes for therapeutic targets (e.g., metabolic disorders, cancer).
• Diagnostic Reagent Manufacturing: Incorporated as a critical component in clinical diagnostic kits for measuring specific enzyme activities related to metabolic health.
• Biochemical Standard: Serves as a purity standard for calibrating analytical instruments like HPLC and LC-MS in lipidomics and metabolomics studies.
• Cell Biology & Signaling: Utilized in research exploring the role of lipid derivatives like stearoyl-CoA in cellular processes such as protein acylation and signal transduction.

Basic Information

Product Name	n-Octadecanoyl Coenzyme A Lithium Salt
CAS No.	193402-48-1
Molecular Formula	C39H68N7O17P3S • xLi
Molecular Weight	~1000.9 g/mol (Free acid)
Synonyms	Stearoyl-Coenzyme A Lithium Salt; Octadecanoyl-CoA Li Salt; CoA C18:0 Lithium Salt; Stearoyl-CoA Lithium Salt; n-Stearoyl Coenzyme A Lithium Salt; C18:0-CoA Lithium Salt; 18:0 CoA Lithium Salt; Octadecanoyl-Coenzyme A Lithium
EINECS	Contact for details

Quality Control

Every batch of n-Octadecanoyl Coenzyme A Lithium Salt is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and suitability for sensitive research applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting results from HPLC, NMR, and MS analysis. Our quality commitment aligns with standards expected for biochemical and pharmaceutical-grade reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.