Description

2,5-Difluorophenylboronic Acid is a high-purity organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce a difluorophenyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, leveraging the fluorine atoms to modulate bioavailability and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting.
• Polymer Chemistry: Employed to create functionalized monomers and specialty polymers with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for constructing complex, fluorinated aromatic compounds.
• Diagnostic Reagent Preparation: Used in synthesizing probes and labeling agents for biochemical assays and imaging.

Basic Information

Product Name	2,5-Difluorophenylboronic Acid
CAS No.	193353-34-3
Molecular Formula	C6H5BF2O2
Molecular Weight	157.92 g/mol
Synonyms	(2,5-Difluorophenyl)boronic Acid; 2,5-Difluorobenzeneboronic Acid; B-(2,5-Difluorophenyl)boronic Acid; 2,5-Difluorophenyl-Boric Acid; 193353-34-3; 2,5-DFPBA
EINECS	Contact for details

Quality Control

Our 2,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.