Description

Methyl 2-(4-Bromo-2-Fluorophenyl)Acetate is a high-purity, versatile arylacetic acid ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of bromo and fluoro substituents on the aromatic ring, which enable selective functionalization and are key to constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the halogenated phenyl moiety for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic electronic materials and liquid crystal compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings to create biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up processes.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	Methyl 2-(4-Bromo-2-Fluorophenyl)Acetate
CAS No.	193290-19-6
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Methyl (4-Bromo-2-fluorophenyl)acetate; 2-(4-Bromo-2-fluorophenyl)acetic acid methyl ester; (4-Bromo-2-fluorophenyl)acetic acid methyl ester; Methyl 4-bromo-2-fluorobenzeneacetate; 4-Bromo-2-fluorobenzeneacetic acid methyl ester; Methyl α-(4-bromo-2-fluorophenyl)acetate; Acetic acid, 2-(4-bromo-2-fluorophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for precise identification and purity verification. Certificates of Analysis (COA) detailing all critical parameters are available upon request for every batch shipped, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.