Description

1-(2-Bromoethoxy)-2-Fluorobenzene is a versatile fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromoethoxy linker and a fluorine substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine and ether functionalities into polymer chains, altering properties like chemical resistance, thermal stability, and surface energy.
• Cross-Coupling Reactions: The bromoethoxy side chain acts as a handle for further functionalization via palladium-catalyzed reactions (e.g., Suzuki, Heck) to create diverse molecular architectures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new synthetic routes and molecular entities.

Basic Information

Product Name	1-(2-Bromoethoxy)-2-Fluorobenzene
CAS No.	193220-21-2
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	2-Fluoro-1-(2-bromoethoxy)benzene; 1-Bromo-2-(2-fluorophenoxy)ethane; 2-(2-Fluorophenoxy)ethyl Bromide; o-Fluorophenoxyethyl Bromide; (2-Bromoethoxy)-2-fluorobenzene; 2-Fluorophenyl 2-bromoethyl ether; Benzene, 1-(2-bromoethoxy)-2-fluoro-
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethoxy)-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.