Description

Benzeneacetic Acid, 4-Amino-3-Fluoro-, Methyl Ester is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine and amino groups can dramatically alter biological activity and metabolic stability. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Fine Chemical Production: Employed in the manufacture of other fluorinated aromatic compounds for electronics and material science applications.
• Bioconjugation and Probe Synthesis: Useful in medicinal chemistry for creating fluorescent probes or bioconjugates for diagnostic and research purposes.
• Academic and Contract Research: A valuable reagent for method development and exploratory research in synthetic organic chemistry laboratories.

Basic Information

Product Name	Benzeneacetic Acid, 4-Amino-3-Fluoro-, Methyl Ester
CAS No.	192650-55-8
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	Methyl 4-Amino-3-fluorophenylacetate; 4-Amino-3-fluorobenzeneacetic Acid Methyl Ester; 3-Fluoro-4-aminophenylacetic Acid Methyl Ester; (4-Amino-3-fluorophenyl)acetic Acid Methyl Ester; Methyl (4-Amino-3-fluorophenyl)acetate; 2-(4-Amino-3-fluorophenyl)acetic Acid Methyl Ester; 192650-55-8; 4-Amino-3-fluoro-α-toluic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 4-Amino-3-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.