Description

(R)-1-[2-(Diphenylphosphino)Phenyl]Ethylamine, Min. 97% is a high-purity chiral phosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, crucial for producing single-isomer intermediates in pharmaceutical and fine chemical synthesis. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst Ligand: A key component in chiral catalysts for the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Used in the production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Manufacturing: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profile.
• Cross-Coupling Reactions: Serves as a ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Academic & Industrial R&D: A valuable tool for method development and discovery chemistry in asymmetric synthesis laboratories.
• Fine Chemical Production: Facilitates the manufacture of specialty chemicals, flavors, and fragrances requiring specific chirality.

Basic Information

Item	Details
Product Name	(R)-1-[2-(Diphenylphosphino)Phenyl]Ethylamine, Min. 97%
CAS No.	192057-60-6
Molecular Formula	C20H20NP
Molecular Weight	305.35 g/mol
Synonyms	(R)-[2-(Diphenylphosphino)phenyl]ethanamine; (R)-1-[2-(Diphenylphosphino)phenyl]ethanamine; (R)-2-(Diphenylphosphino)benzylamine; (R)-2-(Diphenylphosphino)-α-methylbenzylamine; (R)-DIPAMP derivative; (R)-Josiphos-type ligand precursor; (R)-PPFA analog; Chiral atropisomeric phosphine-amine ligand
EINECS	Contact for details

Quality Control

Every batch of (R)-1-[2-(Diphenylphosphino)Phenyl]Ethylamine is produced and tested under strict quality management protocols to ensure consistent high purity and enantiomeric excess. Our rigorous quality testing includes chiral HPLC, NMR, and elemental analysis to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.