Description

Perospirone Hydrochloride Hydrate is a high-purity pharmaceutical active ingredient, specifically an atypical antipsychotic agent. This compound is critical for research and development in neuropsychiatric therapeutics, offering a key building block for formulation studies. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in central nervous system (CNS) drug discovery and generic drug development.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antipsychotic medications.
• Reference Standard: Serves as a certified standard for quality control and analytical method development in pharmaceutical laboratories.
• Biomedical Research: Used in preclinical studies to investigate mechanisms of action related to dopamine and serotonin receptor antagonism.
• Generic Drug Development: Essential for companies developing bioequivalent versions of existing antipsychotic treatments.
• Process Chemistry & Scale-up: Employed in optimizing synthetic routes and manufacturing processes for commercial production.

Basic Information

Product Name	Perospirone Hydrochloride Hydrate
CAS No.	192052-81-6
Molecular Formula	C23H30FN3O2S • HCl • xH2O
Molecular Weight	Anhydrous Free Base: 431.57 g/mol
Synonyms	Perospirone HCl Hydrate; SM-9018; (3aR,4S,7R,7aS)-2-[(4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione Hydrochloride Hydrate; CRM-3010; Lullan (brand name derivative); Perospiron Hydrochloride Hydrate
EINECS	Contact for details

Quality Control

Our Perospirone Hydrochloride Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	As per batch COA
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.