Description

Zolmitriptan Related Compound D (20 Mg) ((S)-Ethyl 3-[2-(Dimethylamino)Ethyl]-5-[(2-Oxooxazolidin-4-Yl)Methyl]-1H-Indole-2-Carboxylate) is a high-purity reference standard and pharmaceutical intermediate critical for quality control and research applications. This compound is essential for ensuring the purity, safety, and efficacy of the active pharmaceutical ingredient Zolmitriptan, a medication used to treat migraine headaches. It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions for method development, validation, and impurity profiling. The product is supplied as a precisely weighed 20 mg quantity, facilitating accurate and convenient use in laboratory settings.

Application

• Pharmaceutical Impurity Profiling and Control: Used as a certified reference material to identify, quantify, and monitor this specific related substance in Zolmitriptan API and finished dosage forms.
• Analytical Method Development and Validation: Serves as a critical standard for developing and validating HPLC, UPLC, or GC methods in quality control laboratories.
• Stability Studies: Employed as a marker compound in forced degradation and long-term stability studies of Zolmitriptan to understand its degradation pathways.
• Regulatory Compliance and Documentation: Essential for preparing regulatory submissions (e.g., for FDA, EMA) that require detailed impurity identification and characterization data.
• Chemical Synthesis Research: Acts as a key intermediate or a comparative standard in the research and development of new synthetic routes for triptan-class pharmaceuticals.
• Quality Assurance/Quality Control (QA/QC): Used for routine batch release testing to ensure Zolmitriptan products meet stringent pharmacopeial (USP, EP) specifications for related substances.

Basic Information

Product Name	Zolmitriptan Related Compound D (20 Mg) ((S)-Ethyl 3-[2-(Dimethylamino)Ethyl]-5-[(2-Oxooxazolidin-4-Yl)Methyl]-1H-Indole-2-Carboxylate)
CAS No.	191864-24-1
Molecular Formula	C21H27N3O4
Molecular Weight	385.46 g/mol
Synonyms	(S)-Ethyl 3-[2-(dimethylamino)ethyl]-5-[(2-oxooxazolidin-4-yl)methyl]-1H-indole-2-carboxylate; Zolmitriptan Impurity D; Zolmitriptan Related Substance D; Zolmitriptan EP Impurity D; Zolmitriptan USP Related Compound D; 1H-Indole-2-carboxylic acid, 3-[2-(dimethylamino)ethyl]-5-[(2-oxo-4-oxazolidinyl)methyl]-, ethyl ester, (S)-; Zolmitriptan Process Impurity
EINECS	Contact for details

Quality Control

Every batch of Zolmitriptan Related Compound D is manufactured and controlled under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC purity assay, related substance analysis, and structural confirmation (IR, NMR, MS), to ensure it meets the high standards required for pharmaceutical reference materials. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment. Our quality commitment aligns with the requirements of major pharmacopeias, supporting your regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C (59-77°F). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.