Description

1,10-Phenanthroline, 5-Fluoro- is a fluorinated derivative of the classic 1,10-phenanthroline chelating ligand. This modification introduces a fluorine atom at the 5-position, significantly altering its electronic properties, coordination behavior, and solubility profile compared to the parent compound. It serves as a critical building block and analytical reagent in advanced materials science and pharmaceutical research. This high-purity intermediate is primarily utilized by researchers and manufacturers in organic synthesis, coordination chemistry, and as a precursor for developing novel catalysts and luminescent materials.

Application

• Coordination Chemistry & Catalyst Development: Acts as a specialized ligand for transition metals, enabling the synthesis of catalysts with tailored activity and selectivity for organic transformations.
• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly where fluorine substitution is desired for metabolic stability.
• Materials Science Research: Used in the design of metal-organic frameworks (MOFs), supramolecular assemblies, and electro-luminescent materials due to its modified photophysical properties.
• Analytical Chemistry Reagent: Functions as a selective chelating agent in spectrophotometric methods for the detection and quantification of specific metal ions.
• Organic Synthesis Building Block: The fluorine atom provides a handle for further functionalization via cross-coupling reactions, making it valuable for constructing complex heterocyclic systems.

Basic Information

Product Name	1,10-Phenanthroline, 5-Fluoro-
CAS No.	191861-19-5
Molecular Formula	C12H7FN2
Molecular Weight	198.20 g/mol
Synonyms	5-Fluoro-1,10-phenanthroline; 5-Fluoro-1,10-phenanthroline; 5-Fluorophenanthroline; 1,10-Phenanthroline, 5-fluoro-; 5-Fluoro-1,10-phenanthroline; 5-Fluoro-1,10-phenanthroline; 5-Fluoro-1,10-phenanthroline; 5-Fluoro-1,10-phenanthroline
EINECS	Contact for details

Quality Control

Our 1,10-Phenanthroline, 5-Fluoro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.