Description

2-Ethenyl-3-Phenyl-2-(Trifluoromethyl)Oxirane is a specialized fluorinated oxirane derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a reactive epoxide ring adjacent to a trifluoromethyl group and vinyl substituent, makes it a critical precursor for introducing fluorinated motifs into target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to enhance the metabolic stability, lipophilicity, and bioavailability of novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of specialty polymers and coatings, imparting unique surface properties, chemical resistance, and durability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Cross-coupling & Click Chemistry: The vinyl group enables further functionalization via metathesis or other coupling reactions, expanding its utility in combinatorial chemistry and library synthesis.
• Asymmetric Synthesis: The chiral center of the oxirane ring makes it a valuable substrate for developing enantioselective catalysts and producing chiral fluorinated compounds.

Basic Information

Product Name	2-Ethenyl-3-Phenyl-2-(Trifluoromethyl)Oxirane
CAS No.	191591-48-7
Molecular Formula	C11H9F3O
Molecular Weight	214.18 g/mol
Synonyms	2-Vinyl-3-phenyl-2-(trifluoromethyl)oxirane; 1-Phenyl-2-(trifluoromethyl)-1,2-epoxy-3-butene; 3-Phenyl-2-(trifluoromethyl)-2-vinyloxirane; 2-(Trifluoromethyl)-2-vinyl-3-phenyloxirane; α-(Trifluoromethyl)-α-vinylstyrene oxide; (2-Trifluoromethyl-2-vinyl-oxiranyl)-benzene; Glycidyl Trifluoromethyl Styrene Derivative
EINECS	Contact for details

Quality Control

Our production of 2-Ethenyl-3-Phenyl-2-(Trifluoromethyl)Oxirane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 standards for quality management in chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactive epoxide functionality, prolonged exposure to heat, moisture, or direct light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.