Description

L-Alanine, 3-Amino-2-Methyl-, Methyl Ester (9Ci) is a specialized, non-proteinogenic amino acid derivative with a chiral center, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of pharmaceuticals, particularly for active pharmaceutical ingredients (APIs) and peptide-based therapeutics. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in oncology and metabolic disease research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce modified alanine residues, enhancing peptide stability and bioactivity.
• Proteomics Research: Employed as a building block for creating custom amino acid analogs to study protein structure, function, and enzyme-substrate interactions.
• Agrochemical Development: Serves as a precursor in the synthesis of chiral herbicides and plant growth regulators.
• Ligand and Catalyst Design: Utilized in the development of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Diagnostic Reagents: A component in the synthesis of contrast agents or molecular probes for medical imaging and diagnostic assays.

Basic Information

Product Name	L-Alanine, 3-Amino-2-Methyl-, Methyl Ester (9Ci)
CAS No.	190393-73-8
Molecular Formula	C5H12N2O2
Molecular Weight	132.16 g/mol
Synonyms	L-3-Amino-2-methylalanine methyl ester; Methyl (2S)-3-amino-2-methylpropanoate; (S)-Methyl 3-amino-2-methylpropanoate; 3-Amino-2-methyl-L-alanine methyl ester; L-3-Amino-2-methyl-alanine methyl ester; Methyl L-3-amino-2-methylalaninate; (S)-3-Amino-2-methylpropionic acid methyl ester
EINECS	Contact for details

Quality Control

Our L-Alanine, 3-Amino-2-Methyl-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.