Description

(R)-3-Methoxymethoxy-Mandelonitrile is a chiral, non-racemic cyanohydrin derivative, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its stereochemical integrity, which is crucial for constructing enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry enhances biological activity and reduces environmental impact.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals, flavors, and fragrances requiring precise stereocontrol.
• Academic & Industrial R&D: A critical reagent for exploring new synthetic routes and for the preparation of target molecules in medicinal chemistry programs.

Basic Information

Product Name	(R)-3-Methoxymethoxy-Mandelonitrile
CAS No.	189683-85-0
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	(R)-α-Hydroxy-3-(methoxymethoxy)benzeneacetonitrile; (R)-2-Hydroxy-2-[3-(methoxymethoxy)phenyl]acetonitrile; (R)-3-(Methoxymethoxy)mandelonitrile; (R)-Mandelonitrile 3-(methoxymethyl) ether; (R)-OMM-Mandelonitrile; (R)-MMM-Cyanohydrin
EINECS	Contact for details

Quality Control

Our (R)-3-Methoxymethoxy-Mandelonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and IR spectroscopy for structural confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.