Description

2-Bromo-5-Hydroxybenzonitrile is a versatile brominated aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications ranging from drug discovery to the development of specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized benzonitrile core.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal Materials: Used in the research and production of advanced display materials due to its rigid, polarizable aromatic structure.
• Polymer Chemistry: Monomer or cross-linking agent for creating high-performance engineering plastics and specialty resins.
• Organic Ligand Synthesis: Intermediate for preparing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions in academic and industrial R&D.

Basic Information

Product Name	2-Bromo-5-Hydroxybenzonitrile
CAS No.	189680-06-6
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	5-Hydroxy-2-bromobenzonitrile; 2-Bromo-5-cyanophenol; 5-Cyano-2-bromophenol; 2-Bromo-5-hydroxybenzenecarbonitrile; 189680-06-6; 5-Hydroxy-2-bromobenzene nitrile; 2-Brom-5-hydroxybenzonitril (German); 2-Bromo-5-idrossibenzonitrile (Italian)
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Hydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.