Description

4'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Amine is a high-purity aromatic amine building block featuring a biphenyl core substituted with a trifluoromethyl group and an amine functionality. This compound is valued for its role as a critical intermediate in advanced organic synthesis, where its unique electronic properties and structural motif are leveraged. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis, enabling novel synthetic transformations.
• Fluorescent Probe and Dye Chemistry: Utilized as a building block for creating fluorophores and molecular probes used in bioimaging and diagnostic assays.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and amination reactions.

Basic Information

Product Name	4'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Amine
CAS No.	189575-70-0
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	2-Amino-4'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-2-amine, 4'-(trifluoromethyl)-; 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine; 2-Amino-4'-trifluoromethylbiphenyl; 4'-Trifluoromethylbiphenyl-2-amine; 2-(4-Trifluoromethylphenyl)aniline
EINECS	Contact for details

Quality Control

Our 4'-(Trifluoromethyl)[1,1'-Biphenyl]-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.