Description

Cortistatin-17 (Human) CAS NO 189450-19-9 is a synthetic peptide fragment of the human cortistatin protein, a neuropeptide with structural and functional similarities to somatostatin. This high-purity reference standard is critical for advancing research in neuroendocrinology and related metabolic studies. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on neuroscience, sleep regulation, and endocrine function.

Application

• Neuroscience Research: Investigation of cortistatin's role in sleep-wake cycles, neural activity, and cortical function.
• Endocrine Studies: Research into the modulation of growth hormone secretion and other pituitary functions.
• Biomarker Development: Use as a reference standard in immunoassays (ELISA, RIA) for quantifying cortistatin levels in biological samples.
• Drug Discovery: Screening and characterization of novel therapeutics targeting somatostatin and cortistatin receptors.
• Academic & Institutional Research: Fundamental biochemical and pharmacological studies in university and government laboratories.
• In Vitro Diagnostics (IVD): Calibration and quality control for diagnostic assays related to neurological or endocrine disorders.

Basic Information

Product Name	Cortistatin-17 (Human)
CAS No.	189450-19-9
Molecular Formula	C94H147N31O26S2
Molecular Weight	2155.5 g/mol
Synonyms	Cortistatin-17; Human Cortistatin (1-17); CST-17; Cortistatin-17 Peptide; Cortistatin-17 (human); Preprocortistatin (104-120) (human); H-Ala-Pro-Ser-Lys-Pro-Ala-Asn-Leu-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-OH (Disulfide bridge: Cys17-Cys17)
EINECS	Contact for details

Quality Control

Every batch of Cortistatin-17 (Human) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder desiccated at -20°C. Reconstituted solutions should be aliquoted and stored at -20°C or -80°C to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.