Description

4-(Benzyloxy)-2-Hydroxybenzonitrile is a versatile aromatic nitrile derivative featuring both benzyl ether and phenolic hydroxyl functional groups. This compound serves as a crucial advanced pharmaceutical intermediate (API) and a valuable building block in synthetic organic chemistry. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators due to its bioactive phenolic nitrile structure.
• Ligand and Catalyst Development: Used in coordination chemistry to create novel ligands for metal-catalyzed cross-coupling and other organic transformations.
• Material Science Research: Intermediate for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for developing fluorescent tags or molecular probes for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-(Benzyloxy)-2-Hydroxybenzonitrile
CAS No.	189439-24-5
Molecular Formula	C14H11NO2
Molecular Weight	225.24 g/mol
Synonyms	2-Hydroxy-4-(phenylmethoxy)benzonitrile; 4-Benzyloxy-2-hydroxybenzonitrile; 2-Cyano-5-(benzyloxy)phenol; Benzonitrile, 4-(benzyloxy)-2-hydroxy-; 189439-24-5; 4-Benzyloxysalicylonitrile; Salicylonitrile, 4-benzyloxy-
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-2-Hydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.