Description

5-Bromothiophene-3-Carboxamide is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is essential for medicinal chemists and R&D professionals developing novel active ingredients, where its unique thiophene scaffold functionalized with bromine and carboxamide groups enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel fungicides, herbicides, and insecticides that leverage the thiophene core for enhanced biological activity.
• Material Science Research: Serves as a precursor for functionalized monomers in the synthesis of conductive polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to the reactivity of the bromine atom for cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing specialized compounds for client R&D programs.

Basic Information

Product Name	5-Bromothiophene-3-Carboxamide
CAS No.	189329-94-0
Molecular Formula	C5H4BrNOS
Molecular Weight	206.06 g/mol
Synonyms	3-Carbamoyl-5-bromothiophene; 5-Bromo-3-thiophenecarboxamide; 5-Bromothiophene-3-carboxylic acid amide; 189329-94-0; 5-Bromothiophene-3-carboxylic acid, amide; Thiophene-3-carboxamide, 5-bromo-
EINECS	Contact for details

Quality Control

Our 5-Bromothiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceability meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.