Description

(R)-(+)-(Diphenylphosphino)-2'-Isopropoxy-1,1'-Binaphthyl CAS NO 189274-36-0 is a chiral, atropisomeric monophosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in a variety of transition metal-catalyzed reactions, enabling the production of single-enantiomer intermediates and active pharmaceutical ingredients (APIs). This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• Catalyst component in asymmetric cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig).
• Key reagent for enantioselective synthesis of chiral pharmaceutical intermediates and natural products.
• Use in asymmetric allylic substitution and hydroformylation reactions.
• Research and development of novel catalytic systems in academic and industrial laboratories.
• Production of optically pure flavors, fragrances, and agrochemicals.

Basic Information

Product Name	(R)-(+)-(Diphenylphosphino)-2'-Isopropoxy-1,1'-Binaphthyl
CAS No.	189274-36-0
Molecular Formula	C₃₅H₂₉O₁P
Molecular Weight	496.58 g/mol
Synonyms	(R)-(+)-2'-Isopropoxy-2-(diphenylphosphino)-1,1'-binaphthyl; (R)-2'-Isopropoxy-2-(diphenylphosphino)-1,1'-binaphthyl; (R)-iPr-BINAP(O); (R)-2-(Diphenylphosphino)-2'-(isopropoxy)-1,1'-binaphthyl; (R)-2'-(Isopropoxy)-2-(diphenylphosphino)-1,1'-binaphthyl; (R)-iPrO-BINAP; (R)-2-Diphenylphosphino-2'-isopropoxy-1,1'-binaphthyl; (R)-iPr-BINAPO
EINECS	Contact for details

Quality Control

Our (R)-(+)-(Diphenylphosphino)-2'-Isopropoxy-1,1'-Binaphthyl is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification. A Certificate of Analysis (COA) detailing purity, identity, and specific parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.