Description

Benzonitrile, 4-Bromo-2,3,5,6-Tetramethyl- is a high-purity, multi-substituted aromatic nitrile building block of significant interest in advanced organic synthesis. Its unique sterically hindered structure, featuring bromine and nitrile functional groups on a tetramethylated benzene core, makes it a valuable precursor for creating complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for constructing sterically hindered biaryl systems and heterocycles.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules, where the bromine atom offers a versatile handle for further cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic catalysis and coordination chemistry.
• Material Science Research: Acts as a monomer or building block for developing novel polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Research & Development: A versatile reagent for method development in organic synthesis, including Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	Benzonitrile, 4-Bromo-2,3,5,6-Tetramethyl-
CAS No.	188984-14-7
Molecular Formula	C11H12BrN
Molecular Weight	238.13 g/mol
Synonyms	4-Bromo-2,3,5,6-tetramethylbenzonitrile; 2,3,5,6-Tetramethyl-4-bromobenzonitrile; 4-Bromo-2,3,5,6-tetramethylphenyl cyanide; p-Bromopentamethylbenzonitrile; Benzonitrile, 4-bromo-2,3,5,6-tetramethyl-; 188984-14-7; 4-Bromo-2,3,5,6-tetramethylbenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Bromo-2,3,5,6-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes results from HPLC, GC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.