Description

2-Chloro-5-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a chloro and a hydroxy substituent on the benzonitrile core, makes it a valuable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptor sites.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal Materials: Serves as a building block for the synthesis of specialized monomers used in liquid crystal displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Intermediate in the creation of electron-transport or host materials for OLED devices.
• Dyestuff and Pigment Manufacturing: Utilized in the synthesis of high-performance, color-fast dyes and organic pigments.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into polymer chains.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel chemical entities in academic and industrial R&D labs.

Basic Information

Product Name	2-Chloro-5-Hydroxybenzonitrile
CAS No.	188774-56-3
Molecular Formula	C7H4ClNO
Molecular Weight	153.56 g/mol
Synonyms	5-Hydroxy-2-chlorobenzonitrile; 2-Chloro-5-cyanophenol; 5-Cyano-2-chlorophenol; 2-Chloro-5-hydroxybenzenecarbonitrile; Benzonitrile, 2-chloro-5-hydroxy-; 2-Chlor-5-hydroxybenzonitril (German); 2-クロロ-5-ヒドロキシベンゾニトリル (Japanese); 2-氯-5-羟基苯甲腈 (Chinese)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Hydroxybenzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.