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D-Threonine(Bzl)-Obzl Oxalate (1:1) CAS NO 188660-14-2
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CAS No.:188660-14-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-Threonine(Bzl)-Obzl Oxalate (1:1) is a protected derivative of the amino acid threonine, specifically formulated as an oxalate salt. This high-purity building block is critical for the synthesis of complex peptides and pharmaceutical intermediates where precise stereochemistry and side-chain protection are required. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for advanced R&D and cGMP production.
Application
- Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic peptides and active pharmaceutical ingredients (APIs).
- Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate protected threonine residues into peptide chains.
- Biochemical Research: Serves as a reagent in proteomics research, enzyme studies, and the development of biochemical probes.
- Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules requiring protected amino acid motifs.
- Reference Standard: Can be used as a high-purity analytical standard for quality control and method development in analytical laboratories.
Basic Information
| Product Name | D-Threonine(Bzl)-Obzl Oxalate (1:1) |
| CAS No. | 188660-14-2 |
| Molecular Formula | C22H25NO7 |
| Molecular Weight | 415.44 g/mol |
| Synonyms | D-Threonine, O-benzyl-, benzyl ester, oxalate (1:1); (2R,3S)-2-Amino-3-[(benzyloxy)methyl]-3-oxopropyl benzoate oxalate; D-O-Benzylthreonine Benzyl Ester Oxalate; H-D-Thr(Bzl)-OBzl oxalate; Fmoc-D-Thr(Bzl)-OH benzyl ester oxalate salt; Boc-D-Thr(Bzl)-OBzl oxalate; D-3-Benzyloxy-2-aminobutanoic acid benzyl ester oxalate |
| EINECS | Contact for details |
Quality Control
Our D-Threonine(Bzl)-Obzl Oxalate (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) with full traceability are provided to ensure compliance with your research or cGMP requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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