Description

1-Boc-4-Methoxypiperidine is a versatile and high-purity protected piperidine derivative, essential as a key synthetic building block in advanced organic synthesis. Its primary value lies in providing a reactive nitrogen center that is protected from unwanted side reactions, enabling precise and efficient multi-step chemical transformations. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and other bioactive molecules containing a piperidine scaffold.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the 4-methoxypiperidine moiety contributes to biological activity.
• Peptidomimetics & Drug Discovery: Serves as a constrained amino acid surrogate or a conformational constraint element in the design of peptide mimics and small molecule drug candidates.
• Ligand & Catalyst Development: Employed as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalization agent in the synthesis of specialized polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, protected heterocyclic intermediates.

Basic Information

Product Name	1-Boc-4-Methoxypiperidine
CAS No.	188622-27-7
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	tert-Butyl 4-methoxypiperidine-1-carboxylate; 4-Methoxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-methoxypiperidine; N-Boc-4-methoxypiperidine; Boc-4-methoxypiperidine; 4-Methoxy-N-Boc-piperidine; 1-Boc-4-methoxy-piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Methoxypiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.