Description

4-Fluoro-3'-Iododiphenyl Ether is a high-purity, diaryl ether derivative featuring strategically positioned halogen substituents. This compound is a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis, valued for its unique reactivity profile. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine and iodine atoms for bioactivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis, such as Suzuki-Miyaura and Buchwald-Hartwig cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, including monomers for conjugated polymers and liquid crystals.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and exploratory synthesis in academic and industrial laboratories.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4-Fluoro-3'-Iododiphenyl Ether
CAS No.	188534-09-0
Molecular Formula	C12H8FIO
Molecular Weight	314.09 g/mol
Synonyms	1-Fluoro-4-(3-iodophenoxy)benzene; 3-Iodophenyl 4-fluorophenyl ether; 4-Fluoro-3'-iododiphenyl ether; 3'-Iodo-4-fluorodiphenyl ether; (3-Iodophenoxy)-4-fluorobenzene; 4-Fluorophenyl 3-iodophenyl ether; 1-Fluoro-4-(3-iodo-phenoxy)-benzene
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3'-Iododiphenyl Ether is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.