Description

Arachidonoyl Coenzyme A (C20:4) Lithium Salt is a high-purity, chemically defined biochemical reagent essential for lipid metabolism research. This compound serves as a critical substrate and intermediate in enzymatic studies, particularly those involving the arachidonic acid cascade and eicosanoid biosynthesis pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for in vitro assays, enzyme kinetics studies, and metabolic pathway analysis.

Application

• Enzymology Research: Key substrate for studying acyl-CoA synthetases, acyltransferases, and other enzymes involved in arachidonic acid metabolism.
• Lipidomics & Metabolomics: Used as a standard or tracer in mass spectrometry-based lipid profiling to investigate inflammatory and signaling pathways.
• Drug Discovery & Screening: Employed in high-throughput assays to identify and characterize inhibitors or activators of enzymes that utilize arachidonoyl-CoA.
• Biochemical Synthesis: Acts as a building block for the in vitro enzymatic synthesis of complex lipids, including phosphatidylinositols and other signaling molecules.
• Cell Biology Studies: Used to investigate the role of lipid-CoA esters in cellular processes such as membrane remodeling, protein acylation, and intracellular signaling.
• Diagnostic Development: Serves as a critical component in the development of clinical diagnostic kits for metabolic disorders related to fatty acid metabolism.

Basic Information

Product Name	Arachidonoyl Coenzyme A (C20:4) Lithium Salt
CAS No.	188174-63-2
Molecular Formula	C₄₁H₆₈N₇O₁₇P₃S • xLi⁺
Molecular Weight	~1060.0 g/mol (Free acid)
Synonyms	Arachidonoyl-CoA, Lithium Salt; Arachidonoyl-Coenzyme A, Lithium Salt; Arachidonic Acid Coenzyme A; 5Z,8Z,11Z,14Z-Eicosatetraenoyl-CoA; CoA(20:4); Arachidonyl-CoA; 20:4 CoA; Eicosatetraenoyl-Coenzyme A
EINECS	Contact for details

Quality Control

Our Arachidonoyl Coenzyme A (C20:4) Lithium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements of research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5%
Solubility	Soluble in water, methanol/water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.