Description

3-Fluoro-4-(Trifluoromethoxy)Benzeneboronic Acid is a high-purity, synthetically valuable organoboron building block. This compound matters for its crucial role in modern cross-coupling reactions, particularly the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of novel active ingredients and functional molecules. Its unique fluorine and trifluoromethoxy substitution pattern makes it a sought-after intermediate for introducing specific physicochemical properties into target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Material Science Research: Employed in the creation of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing properties.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Design: Utilized in the construction of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the global life sciences industry.

Basic Information

Item	Details
Product Name	3-Fluoro-4-(Trifluoromethoxy)Benzeneboronic Acid
CAS No.	187804-79-1
Molecular Formula	C7H5BF4O3
Molecular Weight	223.92 g/mol
Synonyms	[3-Fluoro-4-(trifluoromethoxy)phenyl]boronic acid; (3-Fluoro-4-(trifluoromethoxy)phenyl)boronic acid; Boronic acid, B-[3-fluoro-4-(trifluoromethoxy)phenyl]-; 3-Fluoro-4-trifluoromethoxybenzeneboronic acid; 3-Fluoro-4-(trifluoromethoxy)phenylboronic acid; 4-Trifluoromethoxy-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethoxy)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.