Description

Pyrrolidine, 3-Methyl-1-(Trifluoroacetyl)-, (S)- (9Ci) is a high-value, chiral pyrrolidine derivative characterized by its trifluoroacetyl protecting group and defined stereochemistry. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective organic synthesis to introduce the (S)-3-methylpyrrolidine scaffold.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed reactions.
• Peptidomimetics: Incorporated into the design of peptide-like molecules to enhance stability and bioavailability for drug discovery.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Pyrrolidine, 3-Methyl-1-(Trifluoroacetyl)-, (S)- (9Ci)
CAS No.	187670-59-3
Molecular Formula	C7H10F3NO
Molecular Weight	181.16 g/mol
Synonyms	(S)-3-Methyl-1-(trifluoroacetyl)pyrrolidine; (S)-1-(Trifluoroacetyl)-3-methylpyrrolidine; (S)-N-(Trifluoroacetyl)-3-methylpyrrolidine; (S)-3-Methylpyrrolidine, 1-(trifluoroacetyl)-; 1-(Trifluoroacetyl)-(S)-3-methylpyrrolidine; (S)-3-Methyl-1-(2,2,2-trifluoroacetyl)pyrrolidine; 3-Methyl-1-(trifluoroacetyl)pyrrolidine, (S)-; (S)-3-Methyl-N-(trifluoroacetyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 3-Methyl-1-(Trifluoroacetyl)-, (S)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.