Description

(1-tert-Butoxycarbonylamino-Cyclohexyl)-Acetic Acid is a high-purity Boc-protected amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of a sterically defined cyclohexylglycine moiety, which is essential for modulating the pharmacokinetic properties of target molecules. This compound is particularly vital for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel peptide mimetics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of protease inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Peptidomimetic Synthesis: Used to incorporate constrained, non-natural amino acid structures into peptide backbones to enhance metabolic stability and bioavailability.
• Agrochemical Research: Serves as a building block for creating novel active ingredients with specific stereochemical requirements.
• Chemical Biology & Proteomics: Utilized in the synthesis of activity-based probes and labeled compounds for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high stereochemical purity.
• Academic & Institutional Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	(1-tert-Butoxycarbonylamino-Cyclohexyl)-Acetic Acid
CAS No.	187610-56-6
Molecular Formula	C₁₃H₂₃NO₄
Molecular Weight	257.33 g/mol
Synonyms	Boc-1-Amino-cyclohexaneacetic acid; (1-((tert-Butoxycarbonyl)amino)cyclohexyl)acetic acid; N-Boc-1-amino-1-cyclohexaneacetic acid; 2-(1-((tert-Butoxycarbonyl)amino)cyclohexyl)acetic acid; N-(tert-Butoxycarbonyl)-1-amino-1-cyclohexylacetic acid; (1-(Boc-amino)cyclohexyl)acetic acid; Cyclohexylglycine, N-Boc- derivative; 187610-56-6
EINECS	Contact for details

Quality Control

Our (1-tert-Butoxycarbonylamino-Cyclohexyl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Under these conditions, the product remains stable for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.