Description

Myristoyl Coenzyme A C14:0 Lithium Salt is a high-purity, long-chain fatty acyl-CoA derivative essential for lipid metabolism research. This compound serves as a critical substrate and intermediate in enzymatic studies, particularly for investigating fatty acid oxidation, biosynthesis, and protein acylation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, metabolic pathway analysis, and biochemical assay development.

Application

• Enzymology Research: Key substrate for studying acyl-CoA synthetases, dehydrogenases, and other enzymes involved in mitochondrial β-oxidation.
• Metabolic Studies: Used to investigate lipid metabolism, energy homeostasis, and related disorders in cell-based and in vitro assays.
• Drug Discovery & Screening: Essential reagent for high-throughput screening (HTS) campaigns targeting metabolic enzymes for therapeutic intervention.
• Biochemical Assay Development: Serves as a standard or critical component in diagnostic and research kits for measuring enzyme activity.
• Protein Acylation Studies: Used to explore post-translational modifications, specifically S-myristoylation, and its role in protein function and signaling.
• Academic & Industrial R&D: Fundamental tool for basic research and applied development in biochemistry and molecular biology laboratories worldwide.

Basic Information

Product Name	Myristoyl Coenzyme A C14:0 Lithium Salt
CAS No.	187100-75-0
Molecular Formula	C35H62N7O17P3S • xLi
Molecular Weight	Approx. 977.8 g/mol (Free acid)
Synonyms	Myristoyl-CoA Lithium Salt; Tetradecanoyl-Coenzyme A Lithium Salt; CoA C14:0; C14:0-CoA; Myristoyl-Coenzyme A; Tetradecanoyl-CoA; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(1-oxotetradecyl)sulfanyl]ethyl})amino)propyl]amino}butyl] dihydrogen diphosphate) Lithium Salt; S-Tetradecanoylcoenzyme A Lithium Salt
EINECS	Contact for details

Quality Control

Our Myristoyl Coenzyme A C14:0 Lithium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We adhere to relevant quality guidelines suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot into single-use vials to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% (by acyl-CoA content)
Water Content (KF)	≤ 5%
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.