Description

Pafuramidine is a synthetic diamidine compound with significant pharmacological research interest. This compound matters as a key intermediate and active pharmaceutical ingredient (API) in the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of treatments for infectious diseases. Pafuramidine CAS NO 186953-56-0 represents a high-purity building block for advanced medical research.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in investigational drug formulations.
• Critical research intermediate in the synthesis of novel antiparasitic and antimicrobial agents.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical tool compound for mechanistic studies targeting specific parasitic enzymes and pathways.
• Starting material for the preparation of derivative compounds with optimized pharmacological profiles.
• Component in non-clinical toxicology and pharmacokinetic studies.

Basic Information

Product Name	Pafuramidine
CAS No.	186953-56-0
Molecular Formula	C19H18F3N5O
Molecular Weight	389.37 g/mol
Synonyms	DB289; 2,5-Bis[4-(trifluoromethoxy)phenyl]furan; 2,5-Bis(4-trifluoromethoxyphenyl)furan; 2,5-Bis[4-(trifluoromethoxy)phenyl]furan; Pafuramidine Maleate (salt form); Furamidine Dihydrochloride (related compound); WR 6026 (developmental code)
EINECS	Contact for details

Quality Control

Our Pafuramidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets stringent research-grade specifications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.