Description

n-Boc Histamine is a protected derivative of the biogenic amine histamine, featuring a tert-butoxycarbonyl (Boc) group on the imidazole nitrogen. This compound is a crucial pharmaceutical intermediate and research chemical, valued for its role in peptide synthesis and medicinal chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors for developing novel therapeutics and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of histamine receptor ligands and other bioactive molecules.
• Peptide Synthesis: Used as a protected histamine residue in solid-phase and solution-phase peptide chemistry.
• Medicinal Chemistry Research: Serves as a precursor for creating analogs to study structure-activity relationships (SAR).
• Biochemical Tool Development: Employed in the preparation of labeled compounds for assay development and diagnostic applications.
• Academic & Industrial R&D: Fundamental reagent for investigating histaminergic pathways and signal transduction mechanisms.

Basic Information

Product Name	n-Boc Histamine
CAS No.	186700-06-1
Molecular Formula	C10H17N3O2
Molecular Weight	211.26 g/mol
Synonyms	1H-Imidazole-4-ethanamine, N-[(1,1-dimethylethoxy)carbonyl]-; N-Boc-histamine; N-(tert-Butoxycarbonyl)histamine; tert-Butyl N-[2-(1H-imidazol-4-yl)ethyl]carbamate; Boc-Histamine; Histamine N-Boc derivative; 186700-06-1; 4-(2-Aminoethyl)-1H-imidazole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-Boc Histamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.