Description

3-Amino-5-Methyl-Benzonitrile is a high-purity aromatic nitrile derivative featuring both amino and methyl functional groups, making it a versatile and valuable building block in advanced organic synthesis. Its molecular structure is engineered to facilitate the construction of complex heterocyclic systems and functionalized aromatic compounds critical for modern chemical development. This intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with benzimidazole, quinazoline, or other nitrogen-containing heterocyclic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its amino and cyano groups for structural diversification.
• Dye and Pigment Manufacturing: Serves as a building block for creating advanced colorants and functional dyes due to its reactive aromatic amine functionality.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where tailored electronic properties are needed.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions such as Buchwald-Hartwig amination for creating complex biaryl amine structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	3-Amino-5-Methyl-Benzonitrile
CAS No.	186551-97-3
Molecular Formula	C8H8N2
Molecular Weight	132.16 g/mol
Synonyms	5-Methyl-3-aminobenzonitrile; 3-Amino-5-methylbenzonitrile; 3-Cyano-5-methylaniline; 5-Methyl-3-cyanoaniline; 3-Amino-5-toluonitrile; Benzonitrile, 3-amino-5-methyl-; 5-Methyl-m-aminobenzonitrile; m-Amino-p-tolunitrile
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Methyl-Benzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the high standards required for cGMP and ISO-guided applications in sensitive industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be hygroscopic; keep container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.