Description

3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzonitrile is a high-value, multi-halogenated benzonitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture, featuring chlorine, fluorine, and trifluoromethyl substituents, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with unique optical or electronic properties.
• Organic Electronics: Building block for electron-deficient units in the synthesis of organic semiconductors and non-fullerene acceptors for photovoltaic applications.
• Chemical Biology: Used as a probe or labeling reagent due to its distinct halogenated pattern, which can be leveraged for further functionalization via cross-coupling reactions.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzonitrile
CAS No.	186517-00-0
Molecular Formula	C8H2ClF4N
Molecular Weight	223.56 g/mol
Synonyms	2-Fluoro-3-chloro-6-(trifluoromethyl)benzonitrile; 6-(Trifluoromethyl)-3-chloro-2-fluorobenzonitrile; 3-Chloro-2-fluoro-α,α,α-trifluoro-o-tolunitrile; 2-Cyano-6-chloro-3-fluorobenzotrifluoride; 2-Chloro-6-cyano-3-fluorobenzotrifluoride; 186517-00-0; Benzene, 2-chloro-1-cyano-6-fluoro-3-(trifluoromethyl)-; 3-Chloro-2-fluoro-6-trifluoromethylbenzonitrile
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-Fluoro-6-(Trifluoromethyl)Benzonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.