Description

4-Difluoromethyl-1,3-dioxolan-2-one is a specialized fluorinated cyclic carbonate ester, a high-value intermediate in advanced organic synthesis. This compound is valued for its unique reactivity, serving as a versatile building block for introducing difluoromethyl and carbonate functionalities into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty polymers and electrolytes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethyl group can enhance biological activity and environmental persistence.
• Lithium-Ion Battery Electrolytes: Serves as a potential precursor or additive for formulating high-performance electrolyte solutions, contributing to improved battery stability and performance.
• Specialty Polymer Modifier: Incorporated as a monomer or cross-linking agent to impart specific properties like chemical resistance or low surface energy into polymeric materials.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecules, leveraging its reactive carbonate and fluorine-containing groups.

Basic Information

Product Name	4-Difluoromethyl-1,3-dioxolan-2-one
CAS No.	186098-91-9
Molecular Formula	C4H4F2O3
Molecular Weight	138.07 g/mol
Synonyms	4-(Difluoromethyl)-1,3-dioxolan-2-one; Difluoromethyl Ethylene Carbonate; 1,3-Dioxolan-2-one, 4-(difluoromethyl)-; DFEC (Difluoromethyl Ethylene Carbonate); Ethylene Carbonate, 4-Difluoromethyl-; 4-DFEC; 186098-91-9
EINECS	Contact for details

Quality Control

Our 4-Difluoromethyl-1,3-dioxolan-2-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.