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Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-, 2-Methylhydrazide (9Ci) CAS NO 186032-80-4


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CAS No.:186032-80-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-, 2-Methylhydrazide (9Ci) is a specialized Boc-protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating the controlled synthesis and modification of peptides and other complex molecules, where protecting group chemistry is paramount. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, agrochemicals, and fine chemicals. The product is supplied with a CAS number of 186032-80-4.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected glycine derivative with a hydrazide functional handle.
  • Chemical Biology Research: Employed in the study of protein-protein interactions and the development of enzyme inhibitors or probes.
  • Agrochemical Development: Serves as an intermediate in creating novel herbicides, fungicides, or plant growth regulators.
  • Material Science: Potential monomer or modifier in the synthesis of specialized polymers and dendrimers.
  • Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, high-purity building blocks.

Basic Information

Item Detail
Product Name Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-, 2-Methylhydrazide (9Ci)
CAS No. 186032-80-4
Molecular Formula C8H17N3O3
Molecular Weight 203.24 g/mol
Synonyms Boc-Glycine 2-methylhydrazide; N-(tert-Butoxycarbonyl)glycine 2-methylhydrazide; N-Boc-glycine 2-methylhydrazide; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-methylhydrazide; tert-Butyl (2-(2-methylhydrazinyl)-2-oxoethyl)carbamate; (2-(2-Methylhydrazinyl)-2-oxoethyl)carbamic acid tert-butyl ester
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Quality Control

Our Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-, 2-Methylhydrazide (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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