Description

4-[(3-Chlorophenyl)(Hydroxy)Methyl]Benzonitrile is a versatile benzonitrile derivative and a key chiral building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its chlorophenyl and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its rigid aromatic structure.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-[(3-Chlorophenyl)(Hydroxy)Methyl]Benzonitrile
CAS No.	186000-52-2
Molecular Formula	C14H10ClNO
Molecular Weight	243.69 g/mol
Synonyms	4-[(3-Chlorophenyl)(Hydroxy)Methyl]Benzonitrile; (3-Chlorophenyl)(4-cyanophenyl)methanol; α-(3-Chlorophenyl)-4-cyanobenzyl alcohol; 4-((3-Chlorophenyl)(hydroxy)methyl)benzonitrile; 186000-52-2; Benzonitrile, 4-[(3-chlorophenyl)hydroxymethyl]-; (4-Cyanophenyl)(3-chlorophenyl)methanol
EINECS	Contact for details

Quality Control

Our 4-[(3-Chlorophenyl)(Hydroxy)Methyl]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.