Description

(S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetamide is a high-purity chiral intermediate of significant importance in the synthesis of optically active pharmaceutical compounds. Its value lies in its role as a key building block for introducing specific stereochemistry, which is critical for the biological activity of many modern drugs. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing and producing enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of enantiomerically pure drugs, particularly in antiviral, cardiovascular, and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or auxiliary in asymmetric synthesis to construct complex molecules with high enantiomeric excess (ee).
• Nucleoside Analogue Synthesis: Serves as a protected sugar derivative in the research and production of modified nucleosides for antiviral and anticancer applications.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands where precise stereochemistry is required.
• Process Research & Development (R&D): Utilized in laboratory-scale and pilot-scale studies for route scouting and optimization of API manufacturing processes.
• Academic Research: A valuable compound for studies in organic chemistry, medicinal chemistry, and stereochemistry within university and institutional labs.

Basic Information

Product Name	(S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetamide
CAS No.	185996-33-2
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(4S)-2,2-Dimethyl-1,3-dioxolane-4-acetamide; (S)-(-)-2,2-Dimethyl-1,3-dioxolane-4-acetamide; (S)-2,2-Dimethyl-1,3-dioxolane-4-acetic acid amide; L-Glyceraldehyde Acetonide Acetamide; (S)-Acetamide, 2,2-dimethyl-1,3-dioxolane-4-acetic acid; (S)-Acetonide Glyceraldehyde Acetamide; (4S)-2,2-Dimethyl-1,3-dioxolan-4-ylacetamide
EINECS	Contact for details

Quality Control

Our (S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from chiral HPLC, NMR, and other relevant analytical techniques to guarantee consistent quality and traceability for your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and moisture. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.