Description

Boc-1-Methyl-Dl-Tryptophan is a protected derivative of the amino acid tryptophan, featuring a tert-butoxycarbonyl (Boc) group on the amine and a methyl group on the indole nitrogen. This compound is a crucial building block in peptide synthesis and medicinal chemistry, where it serves as a key intermediate for introducing modified tryptophan residues. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key raw material in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to develop new bioactive molecules.
• Bioconjugation: Can be utilized in the preparation of peptide-protein conjugates or labeled peptides for diagnostic applications.
• Academic Research: Employed in university and institutional labs for studying peptide structure, function, and metabolism.
• Process Development: Used in scaling up synthetic routes for peptide candidates during preclinical and clinical development phases.

Basic Information

Product Name	Boc-1-Methyl-Dl-Tryptophan
CAS No.	185527-65-5
Molecular Formula	C₁₉H₂₆N₂O₄
Molecular Weight	346.42 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-1-methyl-DL-tryptophan; Boc-1-Me-DL-Trp-OH; 1-Methyl-DL-tryptophan N-Boc derivative; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(1-methyl-1H-indol-3-yl)propanoic acid; tert-Butyl (1-methyl-1H-indol-3-yl)methylcarbamate; Boc-N-Me-DL-Trp; N-Boc-1-methyltryptophan
EINECS	Contact for details

Quality Control

Our Boc-1-Methyl-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.