Description

(S)-(+)-(2,6-Dimethyl-3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)Dimethylamine is a high-value, chiral organophosphorus ligand of significant interest in advanced chemical synthesis. Its primary value lies in its ability to act as a highly effective and selective catalyst in asymmetric transformations, enabling the production of enantiomerically pure compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic routes.

Application

• Asymmetric Catalysis: As a key chiral ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, hydroformylation, and cross-coupling reactions.
• Pharmaceutical Intermediate Synthesis: For the production of active pharmaceutical ingredients (APIs) requiring specific chirality, such as certain cardiovascular and central nervous system drugs.
• Agrochemical Manufacturing: In the synthesis of chiral herbicides, fungicides, and insecticides where biological activity is stereospecific.
• Fine Chemical Production: Enabling the synthesis of complex, high-value flavor and fragrance compounds, as well as other specialty chemicals.
• Academic & Industrial R&D: Serving as a critical tool for method development and discovery chemistry in laboratories focused on new catalytic processes.
• Material Science Research: Potential use in the development of chiral polymers or as a component in advanced molecular recognition systems.

Basic Information

Product Name	(S)-(+)-(2,6-Dimethyl-3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)Dimethylamine
CAS No.	185449-86-9
Molecular Formula	C25H24NO2P
Molecular Weight	401.44 g/mol
Synonyms	(S)-BINAPO; (S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl dioxide; (S)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl 1,1'-dioxide; (S)-BINAP dioxide; (S)-BINAP(O); (S)-H-MOP; (S)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene 1,1'-dioxide
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure excellent chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.