Description

(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A] is a high-value chiral organophosphorus compound, serving as a crucial building block in advanced synthetic chemistry. Its primary significance lies in its role as a versatile ligand and catalyst precursor for asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity chiral auxiliaries to drive innovation.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation and cross-coupling reactions.
• As a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) with defined stereochemistry.
• In the development of agrochemicals, such as herbicides and fungicides, requiring enantioselective activity.
• For research into new catalytic systems in academic and industrial laboratories.
• In the synthesis of specialty materials, including liquid crystals and advanced polymers.
• As a precursor for other functionalized organophosphorus compounds used in medicinal chemistry.

Basic Information

Product Name	(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A]
CAS No.	185449-81-4
Molecular Formula	C8H9O2P
Molecular Weight	168.13 g/mol
Synonyms	(S)-(+)-2,2-Dimethyl-4-phenyl-1,3,2-dioxaphospholane; (S)-(+)-2-Phenyl-1,3,2-dioxaphospholane 2-oxide; (S)-(+)-Phenylphosphonic acid ethylene ester; (S)-Phenyl-1,3,2-dioxaphospholane 2-oxide; (S)-2-Phenyl-2-oxo-1,3,2-dioxaphospholane; (S)-Phenylphosphonous acid cyclic ethylene ester; DIOXAPHOS ligand precursor; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.