Description

2-Hydroxymethyl-9-[β-D-Ribofuranosyl]Hypoxanthine is a modified nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or reference standard for the creation of novel antiviral and anticancer therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry. The product is supplied with a high level of purity to meet the stringent requirements of these applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside analog drugs.
• Antiviral Research: Used in the development and study of potential antiviral agents targeting viral polymerases.
• Oncology Research: Investigated as a precursor for chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Functions as a substrate or inhibitor in enzymatic studies related to purine metabolism.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex nucleoside derivatives.

Basic Information

Item	Details
Product Name	2-Hydroxymethyl-9-[β-D-Ribofuranosyl]Hypoxanthine
CAS No.	185377-94-0
Molecular Formula	C11H14N4O6
Molecular Weight	298.25 g/mol
Synonyms	2-(Hydroxymethyl)inosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(hydroxymethyl)-1,9-dihydro-6H-purin-6-one; 2-Hydroxymethylinosine; 2-Hydroxymethyl-9-β-D-ribofuranosylhypoxanthine; Modified Inosine Derivative
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-9-[β-D-Ribofuranosyl]Hypoxanthine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a Certificate of Analysis (COA) with every shipment, detailing all specified parameters to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.