Description

4-(Benzyloxy)-1-Bromo-2-Fluorobenzene is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated benzyloxy structure, which facilitates selective coupling reactions and the introduction of functional complexity into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and Industrial R&D: Used in exploratory chemistry for constructing complex molecular architectures in medicinal chemistry and chemical biology programs.

Basic Information

Product Name	4-(Benzyloxy)-1-Bromo-2-Fluorobenzene
CAS No.	185346-79-6
Molecular Formula	C₁₃H₁₀BrFO
Molecular Weight	281.12 g/mol
Synonyms	1-Bromo-4-(benzyloxy)-2-fluorobenzene; 2-Fluoro-4-benzyloxybromobenzene; 4-Benzyloxy-2-fluorobromobenzene; 2-Fluoro-1-bromo-4-(phenylmethoxy)benzene; 1-Bromo-2-fluoro-4-(phenylmethoxy)benzene; Benzene, 1-bromo-4-(benzyloxy)-2-fluoro-; (2-Fluoro-4-bromophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-1-Bromo-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.