Description

Boc-L-2-Nitrophenylalanine is a protected amino acid derivative featuring a Boc (tert-butoxycarbonyl) group and a nitro-substituted phenyl ring. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, where it introduces specific structural and electronic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the non-canonical 2-nitrophenylalanine residue into peptide chains.
• Proteomics Research: Serves as a building block for creating custom peptides used in biochemical assays, enzyme substrate studies, and protein-protein interaction research.
• Agrochemical Development: Employed in the research and synthesis of novel peptide-based pesticides and plant growth regulators.
• Chemical Biology Tool: Utilized to create probes and labeled peptides for studying biological pathways and cellular processes.
• Material Science: A precursor for designing functionalized polymers and advanced materials with specific chemical functionalities.

Basic Information

Product Name	Boc-L-2-Nitrophenylalanine
CAS No.	185146-84-3
Molecular Formula	C₁₄H₁₈N₂O₆
Molecular Weight	310.30 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(2-nitrophenyl)propanoic acid; N-(tert-Butoxycarbonyl)-2-nitro-L-phenylalanine; Boc-2-NO₂-Phe-OH; Boc-L-2-NO₂-Phe-OH; N-Boc-2-nitrophenylalanine; tert-Butyl (2S)-2-amino-1-hydroxy-3-(2-nitrophenyl)-1-oxopropan-2-ylcarbamate; L-2-Nitrophenylalanine, N-Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-L-2-Nitrophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. We provide Certificates of Analysis (COA) with detailed specifications for all critical parameters, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.