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Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 CAS NO 184951-46-0
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CAS No.:184951-46-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 is a synthetic, high-purity peptide sequence derived from the amyloid β-protein, a key component in Alzheimer's disease research. This compound is specifically engineered with a poly-lysine linker to enhance solubility and conjugation capabilities, making it an invaluable tool for biochemical studies. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on neurodegenerative disease mechanisms and therapeutic target validation.
Application
- Biochemical Research: Used as a critical antigen or standard in Alzheimer's disease-related studies, including aggregation kinetics and protein interaction assays.
- Immunoassay Development: Serves as a coating antigen or calibrator in the development of ELISA and other immunoassays for detecting amyloid β-related biomarkers.
- Antibody Production & Screening: Acts as an immunogen for generating and characterizing monoclonal or polyclonal antibodies specific to the amyloid beta (15-25) epitope.
- Drug Discovery Platforms: Employed in high-throughput screening (HTS) assays to identify potential inhibitors of amyloid beta aggregation or toxicity.
- Diagnostic Reagent Manufacturing: Incorporated as a key raw material in the production of in-vitro diagnostic (IVD) reagents and research-use-only (RUO) kits.
- Conjugation & Bioconjugation: The poly-lysine tail facilitates easy conjugation to carrier proteins, fluorescent dyes, or solid supports for various experimental setups.
Basic Information
| Product Name | Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 |
| CAS No. | 184951-46-0 |
| Molecular Formula | C99H174N30O23 |
| Molecular Weight | Contact for details |
| Synonyms | Amyloid β-Protein (15-25), Glycine conjugate; Aβ(15-25)-Gly-(ε-Acp-Lys)6; KLH-Conjugated Amyloid β (15-25) Peptide; Poly-Lysine Linked Aβ(15-25); Synthetic Amyloid Beta Peptide Fragment; Conjugation-Ready Aβ Peptide; Research Grade Aβ(15-25); ε-Aminocaproyl Polylysine Amyloid Beta Peptide |
| EINECS | Contact for details |
Quality Control
Every batch of Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA), detailing purity, peptide content, and solvent residues, is provided with each shipment to guarantee traceability and consistency for your critical research applications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (MS) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 70% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Amino Acid Analysis | Conforms |
| Solvent Residues | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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