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Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 CAS NO 184951-46-0


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CAS No.:184951-46-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 is a synthetic, high-purity peptide sequence derived from the amyloid β-protein, a key component in Alzheimer's disease research. This compound is specifically engineered with a poly-lysine linker to enhance solubility and conjugation capabilities, making it an invaluable tool for biochemical studies. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on neurodegenerative disease mechanisms and therapeutic target validation.

Application

  • Biochemical Research: Used as a critical antigen or standard in Alzheimer's disease-related studies, including aggregation kinetics and protein interaction assays.
  • Immunoassay Development: Serves as a coating antigen or calibrator in the development of ELISA and other immunoassays for detecting amyloid β-related biomarkers.
  • Antibody Production & Screening: Acts as an immunogen for generating and characterizing monoclonal or polyclonal antibodies specific to the amyloid beta (15-25) epitope.
  • Drug Discovery Platforms: Employed in high-throughput screening (HTS) assays to identify potential inhibitors of amyloid beta aggregation or toxicity.
  • Diagnostic Reagent Manufacturing: Incorporated as a key raw material in the production of in-vitro diagnostic (IVD) reagents and research-use-only (RUO) kits.
  • Conjugation & Bioconjugation: The poly-lysine tail facilitates easy conjugation to carrier proteins, fluorescent dyes, or solid supports for various experimental setups.

Basic Information

Product Name Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6
CAS No. 184951-46-0
Molecular Formula C99H174N30O23
Molecular Weight Contact for details
Synonyms Amyloid β-Protein (15-25), Glycine conjugate; Aβ(15-25)-Gly-(ε-Acp-Lys)6; KLH-Conjugated Amyloid β (15-25) Peptide; Poly-Lysine Linked Aβ(15-25); Synthetic Amyloid Beta Peptide Fragment; Conjugation-Ready Aβ Peptide; Research Grade Aβ(15-25); ε-Aminocaproyl Polylysine Amyloid Beta Peptide
EINECS Contact for details

Quality Control

Every batch of Gly-Amyloid β-Protein (15-25)-Gly-ε-Aminocaproyl(-Lys)6 is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA), detailing purity, peptide content, and solvent residues, is provided with each shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (MS) Conforms
Purity (HPLC) ≥ 95%
Peptide Content ≥ 70%
Single Impurity (HPLC) ≤ 1.0%
Amino Acid Analysis Conforms
Solvent Residues Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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